Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm pam3csk4-biotin cas 1429504-10-8 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo zoo pam3csk4-biotin cas 1429504-10-8 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1429504-10-8; Pam3CSK4-Biotin |
| Ib ntus | {(Pam3)Cys}-SKKK-{Lys(Aca-Aca-Biotin)} |
| Peb tsab ntawv ib ntus | |
| Peptide purity (HPLC, %) | 95%/99% |
| Cov mis mos molecular | C103H192N14O17S2 |
| Molecular Luj (Da) | 1962.84 |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Amino Acid Tag Nrho Lub Npe Sequence | Molecular Formula | Qhov hnyav Molecular (Da) | Qhov Nruab Nrab Molecular Luj (Da) | Terminal Hloov kho - N-terminus | Terminal Hloov kho - C-terminus | Qhov ntev (aa) |
| Pam3CSK4-Biotin | #Pam3CSK4-Biotin #TLR2/1 ligand; #Biotinylated lipopeptide; # Innate tiv thaiv kab mob activating peptide | TLR1/TLR2 receptor activation, innate immune signaling pathway, NF-κB activation, immune cell stimulation, streptavidin affinity enrichment, pathogen pattern recognition receptor tshawb fawb | Tripalmitoyl-Cysteine-Serine-Serine-Lysine-Biotin | C₉₀H₁₆₉N₁₃O₁₆S₃ | 1792.215 | 1793.67 | N-terminal tripalmitoyl lipid hloov kho, C-terminal biotin hloov kho | Dawb carboxyl pawg | 4 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv luv -Lub Sijhawm Cia Cia | Kua Stability | Khoom hmoov ruaj khov |
| PEB-PAM-BIO01 | Dawb hmoov | -20℃, lub teeb- pov thawj nitrogen- ntim ntim aliquot ntim, zam tripalmitoyl oxidation thiab biotin photodegradation, txwv tsis pub rov qab khov-thaw cycles | Khaws ntawm 2-8℃hauv qab nitrogen thiab tiv thaiv lub teeb, siv li ntawm 1 lub hlis, npaj tshiab ua ntej kev sim | ruaj khov rau 12 h ntawm 4℃tsis muaj teeb; Nws yooj yim rau oxidation thiab degradation nyob rau hauv siab kub los yog illumination | ruaj khov rau 3 xyoos ntawm -20℃nyob rau hauv lub teeb-pov thawj nitrogen foob, 2 xyoos ntawm 4℃deb ntawm lub teeb |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov Cheeb Tsam Tshawb Fawb (comma- cais) | Hom phiaj / Receptor |
| PEB-PAM-BIO01 | Pam3CSK4-Biotin yog lipidated biotin-tagged TLR1/2 agonist los qhib txoj hauv kev tiv thaiv kab mob hauv lub cev, thov rau receptor affinity capture thiab hauv vitro immune signaling mechanism tshawb fawb | Pam3CSK4-Biotin yog hluavtaws lipopeptide nrog N-terminal tripalmitoyl lipid hloov kho thiab C-terminal biotin daim ntawv lo, ua raws li cov agonist tshwj xeeb rau TLR1/TLR2 heterodimer. Nws nkoos macrophages thiab dendritic hlwb ua rau MyD88-dependent cascade, induces NF-κB nuclear translocation thiab pro{12}}inflammatory cytokine secretion. C-terminal biotin khi streptavidin resin rau rub-down enrichment ntawm TLR2 interacting proteins. Dav siv rau kev tshuaj ntsuam receptor interactome, hauv vitro kev tshuaj ntsuam ntawm TLR pathway inhibitors, innate immune cell activation model thiab pathogen pattern recognition studies, haum rau immunopharmacology, innate immunology thiab receptor proteomics tshawb fawb | Innate immunology, TLR1/TLR2 signaling pathway, macrophage activation, NF-κB inflammatory cascade, receptor affinity purification, immune inhibitor tshuaj ntsuam xyuas | TLR1/TLR2 heterodimer receptor, MyD88 adapter protein, streptavidin, NF-κB transcription factor |
Cim npe nrov: Tuam Tshoj pam3csk4-biotin cas 1429504-10-8 manufacturers, lwm tus neeg, Hoobkas
