Ac -MBP(1-11) CAS 125366-42-9

Khoom Lub Npe Lus Askiv

Product Abbreviation / Alias

Function Tags (comma-sib cais)

Amino Acid Tag Nrho Lub Npe Sequence

Molecular Formula

Qhov hnyav Molecular (Da)

Qhov Nruab Nrab Molecular Luj (Da)

Terminal Hloov kho - N-terminus

Terminal Hloov kho - C-terminus

Qhov ntev (aa)

Ac -MBP(1-11)

#Ac-MBP1-11 #Myelin autoantigen peptide; # Ntau yam sclerosis autoepitope; #T cell activation tshawb fawb peptide

autoimmune antigen, myelin yooj yim protein epitope, ntau yam sclerosis qauv, CD4+ T cell ua, autoimmune o, kev tshawb fawb tiv thaiv kab mob

Acetyl-Serine-Serine-Lysine-Serine-Serine-Leucine-Serine-Arginine-Valine-Proline-Arginine

C₅₇H₁₀₄N₂₂O₂₄

1440.745

1441.56

Kev hloov kho acetylation

Dawb carboxyl pawg

11

Khoom Code

Qhov tshwm sim

Pom zoo Dissolution Protocol (los ntawm hnyav)

Solubility Reference

Tsis pom zoo Solvents

Ntev - Lub Sij Hawm Cia Cov Cai

Luv -Lub Sijhawm Cia Cov Cai

Kua Stability

Khoom hmoov ruaj khov

Muaj feem xyuam pH Range

PEB-MBP01

Dawb lyophilized hmoov

Dilute acetic acid, dej ultrapure; Tsawg solubility nyob rau hauv nruab nrab cov dej ntshiab, ntxiv glacial acetic acid los txhim kho solubility

Ntau dua lossis sib npaug li 10mg / mL hauv 0.1% aqueous acetic acid

Tsis muaj dej ntshiab, alkane organic solvents

-20 degree, kaw kom deb ntawm lub teeb, aliquoted, tsis txhob rov khov-thaw

2-8 degree, siv hauv 1 lub hlis; npaj tshiab ua ntej kev sim

Ruaj khov rau 24 teev ntawm 4 degree

3 xyoos ntawm -20 degree, 2 xyoos ntawm 4 degree

3.0-7.0

Khoom Code

Frontend Short Summary (rau cov npe tshawb nrhiav)

Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg

Cov cheeb tsam tshawb fawb (comma- cais)

Hom phiaj / Receptor

PEB-MBP01

Acetylated MBP (1-11) yog classic myelin autoimmunity epitope uas induces tej CD4+ T cell teb, siv los tsim ntau yam sclerosis autoimmune pathological qauv

Ac-MBP(1-11) yog N-terminally acetylated immunodominant epitope ntawm myelin cov protein. Nws tau nthuav tawm zoo los ntawm MHC chav kawm II molecules thiab tshwj xeeb ua rau myelin-reactive CD4+ pab T hlwb, ua rau autoimmune o hauv nruab nrab paj hlwb. Ua haujlwm raws li tus qauv antigen substrate rau hauv vitro lymphocyte proliferation, cytokine secretion thiab autoantibody nrhiav kom tau. Dav siv rau kev tshawb fawb txog ntau yam sclerosis pathogenesis, kev tiv thaiv kab mob, hauv vitro kev tshuaj ntsuam xyuas ntawm cov tshuaj tiv thaiv kab mob thiab cov qauv ntawm tes rau kev sim autoimmune encephalomyelitis (EAE), tsim nyog rau cov kab mob autoimmune thiab kev tshawb fawb neuroimmunology.

Neuroimmunology, kab mob autoimmune, ntau yam sclerosis, myelin antigen epitope, CD4+ T cell activation, tshuaj tiv thaiv kab mob

MHC class II molecules, CD4+ T cell receptor, MBP- tshwj xeeb autoantibodies

Khoom Code

Purity Detection Method

Molecular Weight Verification Method

Kev Tswj Xyuas Qhov Ntsuas

Impurity Control Standards

PEB-MBP01

Rov qab-theem HPLC

ESI-MS Mass Spectrometry

Purity, dej ntsiab lus, acetate ntsev, hnyav hlau

Ib qho impurity Tsawg dua lossis sib npaug li 2%, tag nrho impurities Tsawg dua lossis sib npaug li 5%

SKU Unique Code

Yam khoom Code

HPLC Purity

Ntim Specification

Lub Sijhawm Ua Haujlwm Ntau Lawm

Customizable

Optional Custom Modifications

Cov ntaub ntawv suav nrog

PEB-MBP01-98-1

PEB-MBP01

Ntau dua lossis sib npaug li 98%

1mg ib

3-7 hnub ua haujlwm

Yog lawm

Fluorescent labeling, biotin labeling, C-terminal amidation

CoA, HPLC chromatogram, MS mass spectrum

PEB-MBP01-98-5

PEB-MBP01

Ntau dua lossis sib npaug li 98%

5mg ib

3-7 hnub ua haujlwm

Yog lawm

Fluorescent labeling, biotin labeling, C-terminal amidation

CoA, HPLC chromatogram, MS mass spectrum

PEB-MBP01-95-1

PEB-MBP01

Ntau dua lossis sib npaug li 95%

1mg ib

3-7 hnub ua haujlwm

Yog lawm

Fluorescent labeling, biotin labeling, C-terminal amidation

CoA, HPLC chromatogram, MS mass spectrum