Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas: 58-49-1: angiotensin ii 5-valine hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas: 58-49-1: angiotensin ii 5-valine los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 58-49-1: Angiotensin II 5-valine |
| Kev piav qhia | Angiotensin II yog cov tseem ceeb effector peptide ntawm renin -angiotensin-aldosterone system (RAAS). Los ntawm tshwj xeeb khi rau AT₁ receptors nyob rau hauv vascular du nqaij, lub raum thiab adrenal cov ntaub so ntswg, nws mediates muaj zog vasoconstriction, txhawb aldosterone synthesis thiab tso tawm, txhim khu lub raum tubular sodium reabsorption thiab elevates ntshav siab, thiab kuj koom nyob rau hauv pathological dab xws li vascular remodeling, inflammatory teb thiab fibrosis. 5-valine yog ib hom tib neeg ib txwm ua raws li kev ua haujlwm siab nrog endogenous human angiotensin II. Nws yog cov cuab yeej classic peptide rau cov kws kho mob plawv, ntshav siab mechanism thiab RAAS kev ua haujlwm kev tshawb fawb, thiab kuj tau siv dav hauv cov tshuaj tiv thaiv kev mob ntshav siab lub hom phiaj kev tshuaj ntsuam xyuas thiab kev ntsuas kev ua tau zoo. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Cov mis mos molecular | C₅₀H₇₁N₁₃O₁₂ |
| Molecular Luj (Da) | 1046.18 |
| Hom qauv | Linear octapeptide, haiv neeg sib lawv liag, dawb daim ntawv / acetate |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Angiotensin II 5-valine | Angiotensin II (Val⁵) | AT₁/AT₂ receptor agonist, vasoconstrictive & hypertensive, RAAS system tshawb fawb cov cuab yeej | Ntuj octapeptide vasoactive peptide, tib neeg sib lawv liag nrog valine ntawm txoj hauj lwm 5, linear unmodified, core effector ntawm renin -angiotensin system | C₅₀H₇₁N₁₃O₁₂ | 1045.54 | 1046.18 | Dawb daim ntawv / acetate | 8 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-ANG201 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot kom tsis txhob rov qab khov-thaw mus. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; nkoj ntawm cov pob khov nab kuab pom zoo. | ruaj khov rau 7 hnub ntawm 4 degree. Dawb soluble nyob rau hauv dilute acetic acid thiab acidic buffers; me ntsis dej solubility. Cov tshuaj aqueous yog degraded sai sai los ntawm peptidases; npaj tshiab ua ntej siv. | ruaj khov rau 3 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-ANG201 | Core effector peptide ntawm RAAS system nrog lub zog vasoconstrictive thiab hypertensive teebmeem | Angiotensin II yog cov tseem ceeb effector peptide ntawm renin -angiotensin-aldosterone system (RAAS). Los ntawm tshwj xeeb khi rau AT₁ receptors nyob rau hauv vascular du nqaij, lub raum thiab adrenal cov ntaub so ntswg, nws mediates muaj zog vasoconstriction, txhawb aldosterone synthesis thiab tso tawm, txhim khu lub raum tubular sodium reabsorption thiab elevates ntshav siab, thiab kuj koom nrog rau hauv pathological dab xws li vascular remodeling, inflammatory teb thiab cov ntaub so ntswg fibrosis. Val⁵ sequence yog haiv neeg txawv teb chaws nrog kev ua tau zoo raws li endogenous human angiotensin II. Nws yog cov cuab yeej classic peptide rau cov kws kho mob plawv, ntshav siab mechanism thiab RAAS kev ua haujlwm kev tshawb fawb, thiab kuj tau siv dav hauv cov tshuaj tiv thaiv kev mob ntshav siab lub hom phiaj kev tshuaj ntsuam xyuas thiab kev ntsuas kev ua tau zoo. | Kev tshawb fawb txog kev mob ntshav siab, RAAS txoj haujlwm ua haujlwm, kev tshawb fawb txog tshuaj kho plawv, tshuaj tiv thaiv kab mob ntshav siab & tshuaj ntsuam xyuas, vascular remodeling & fibrosis tshawb fawb | Angiotensin II hom 1 receptor (AT₁R), hom 2 receptor (AT₂R); Vasoconstriction thiab dej -sodium metabolism kev tswj txoj hauv kev |
Cim npe nrov: CAS: 58-49-1: angiotensin ii 5-valine, Tuam Tshoj cas: 58-49-1: angiotensin ii 5-valine manufacturers, lwm tus neeg, Hoobkas
